Bacteriophages - Hom thiab lub hom phiaj

Qhov tsuas yog siv lwm txoj hauv kev siv cov tshuaj tua kab mob los ntawm cov kab mob pathogenic mus rau hnub tim yog phaj lossis bacteriophages. Lawv yog cov kab mob tshwj xeeb uas xaiv ua rau ntau hom microbes. Muaj ntau pawg neeg paub cov tshuaj, uas yog cov kab mob bacteriophages raug faib - hom thiab lub hom phiaj ntawm cov kab mob no yog lub hauv paus rau kev faib tawm dav dav.

Cov kab mob bacteriophages yog dab tsi?

Muaj 19 tsev neeg muaj kab mob vev tas. Lawv txawv ntawm hom nucleic acid (RNA los yog DNA), genome qauv thiab daim ntawv.

Hauv kev kho mob, bacteriophages tau dej num raws li tus nqi ntawm kev puas tsuaj ntawm cov kab mob pathogenic:

1. Kab mob. Tus kab mob, nkag mus rau hauv lub hlwb ntawm microbes, pib sai thiab nquag muab, yuav luag instantly ua rau tuag ntawm cov kab mob (cov nyhuv lytic).
2. Ntsig. Bacteriophages qeeb thiab tsuas yog ua rau lub cev ntawm cov kab mob pathogenic, tab sis ua rau tsis hloov ntawm lawv, uas kis tau mus rau lwm tiam tom ntej ntawm microbes (cov nyhuv lysogenic).

Niaj hnub no, qhov piav qhia txog hom kab mob vev yog siv ua lwm hom tshuaj tua kab mob rau kev kho mob ntawm ntau hom kab mob bacterial infections. Ntawm lawv cov txiaj ntsig, nws yog ib qho tseem ceeb teev cov txiaj ntsim nram no:

1. Yooj yim daim ntawv tso tawm. Bacteriophages yog tsim nyob rau hauv cov ntsiav tshuaj thiab nyob rau hauv daim ntawv ntawm ib tug tov rau qhov ncauj administration.
2. Tsawg dua cov kev mob tshwm sim. Tsis zoo li cov tshuaj tua kab mob, cov kab mob bacteriophages feem ntau ua rau cov kev ua xua tshwm sim, tsis txhob tsim teeb meem rau lwm yam hauv lub cev.
3. Tsis muaj microbial tsis kam. Cov kab mob nyhav nyuab nyuab dua rau cov kab mob, thiab cov teebmeem nyuaj ua rau tsis yooj yim.

Muaj qee qhov tsis zoo:

• ntev dua ntawm kev khomob (txog 20 hnub);
• teeb meem nrog xaiv ntawm pab pawg neeg ntawm cov yeeb tshuaj;
• hloov ntawm cov kab mob genome los ntawm ib qho microbe mus rau lwm qhov.

Hom bacteriophages thiab lawv siv

Muab qhov tseem ceeb ntawm cov kab mob uas tau piav qhia, hauv cov tshuaj, cov roj thiab cov kab mob uas muaj ntau hom kab mob ntawm cov kab mob no.

Ntawm no, dab tsi yog bacteriophages - sau thiab piav qhia:

1. Mob plab. Muaj kev cuam tshuam rau cov kab mob ntawm typhoid fever, salmonella.
2. Dysfag, dysentery polyvalent. Siv cov kab mob dysentery, ua rau kev tuag ntawm Shigella Sonne thiab Flexner.
3. Klebsifag, Klebsiella pneumonia. Pab nyob rau hauv kev kho mob ntawm cov kab mob ntawm urogenital, digestive, pa system, generalized septic pathologies, phais mob cov tshuaj mob provoking by pneumonia klebsiella .
4. Klebsiellezny polyvalent. Nws yog ib txoj kab tshuaj uas rhuav tshem Klebsiella tsis yog mob ntsws xwb, tab sis kuj rhinoscleromas, ozena.
5. Colitis, yog tias. Txij rau txoj kev kho mob ntawm cov kab mob hauv nruab nrog cev thiab cov tawv nqaij los ntawm E. coli enteropathogenic E. coli.
6. Coliproteophage, coliprotein. Nws adversely cuam tshuam cov kab mob enteropathogenic Proteus thiab Escherichia. Nws yog npaj rau kev kho mob ntawm txoj hlab plawv, cystitis, colitis, pyelonephritis thiab lwm cov kab mob uas tau raug mob los ntawm plab hnyuv plab thiab prost.
7. Proteophagus, Protean Ua rau kev tuag ntawm qee cov proteus microbes mirabilis thiab vulgaris, uas yog cov neeg ua hauj lwm causative purulent inflammatory pathologies ntawm cov hnyuv.
8. Pseudomonas aeruginosa. Tshau cov kab mob pseudomonas aeruginosis. Nws raug nquahu kom dysbiosis, nrog rau kev kho mob ntawm cov kab mob hauv lub cev ntau los ntawm Pseudomonas aeruginosa.
9. Staphylophage, staphylococcus. Mob ceev nrooj los kho cov kab mob staphylococci, uas tau tso tawm los ntawm cov kab mob dawb huv.
10. Streptophagus, qhov mob stroke. Zoo sib xws li kev txiav txim siab rau cov kab mob yav dhau los, tab sis yog tiv thaiv cov kab mob hauv streptococci.
11. Intersti. Nws yog ib txoj kev npaj cov kab mob salmonella, shigella, E. coli , staphylococcus, enterococci, pseudomonas aeruginosa thiab proteus.
12. Piopolyphage, ua ke piobacteriophage. Cov kev kho mob zoo li cov hom kab mob yav dhau los, tab sis nws tseem siv tau los ntawm cov kab mob hauv streptococci.
13. Sextapage, pyobacteriophagous polyvalent. Tsis tas li ntawd tua escherichia coli.
14. Complex piobacteriophage. Kev sib tov ntawm phagolysates ntawm enterococci, streptococci, staphylococci, vulgaris thiab mirabilis protease, klebsiella oxytoca thiab pneumonia, escherichia coli, pseudomonas aeruginosis.