Kev mob txhav yog qhov yog ib qho ntawm cov kab mob ntau tshaj ntawm cov kab mob musculoskeletal. Thiab raws li, tshaj li txoj kev kho mob, nws cov kws kho mob tshwj xeeb yuav tsum xav txog feem ntau txaus. Raws li kev xyaum tau qhia, bisphosphonates rau cov kev kho mob ntawm cov kab mob hauv qab no yog tsim kom zoo li zoo tau. Cov pab pawg ntawm cov tshuaj tau paub tias yog tshuaj rau txij thaum nruab nrab ntawm XIX caug xyoo, tab sis nws yog ua tau kom tau txais ntau yam kev sib hloov tsis ntev los no.
Cov tshuaj-bphphosphonates
Qee cov sib txuas ntawm bisphosphonates tau ntev siv los tiv thaiv kev tiv thaiv corrosion. Lawv feem ntau siv nyob rau hauv cov roj thiab textile industries. Niaj hnub no bisphosphonates tau muaj kev tswj hwm los ua lub hauv paus ntawm kev kho mob tshuaj. Lawv yog cov ntsev ntawm phosphorus, uas pab txhawb rau cov pob txha ntawm cov pob txha thiab kev tiv thaiv ntawm nws qhov kev puas tsuaj. Hais tias yog, cov tshuaj zoo li tau tshwj xeeb tsim rau kev kho mob ntawm osteoporosis.
Ntxiv rau kev ntxiv dag zog, bacterialphonates tsim ib qho tshuaj loog thiab tshuaj tua kabmob antitumor. Ua tsaug rau qhov no, kev siv tshuaj kho kab mob ntsws yog siv rau kev pob txha thiab cov thawj hyperparathyroidism. Thiab lub peev xwm los ua haujlwm ntawm lub hlwb malignant ua rau nws siv tau cov tshuaj hauv oncology, nrog los ntawm ib tug weakening ntawm cov pob txha zog.
Cov tshuaj lom kab mob ntsev li cas yog siv rau txha?
Tag nrho bisphosphonates yuav tsum conditionally muab faib ua ob pawg loj:
- uas muaj nyob hauv cov dej pauv ntawm nitrogen;
- dawb los ntawm nitrogen.
Cov npe ntawm cov tshuaj nrov tshaj plaws zoo li no:
- Bondronate tau sau tseg rau kev kho mob thiab kev tiv thaiv ntawm txha. Tsis zoo li ib co yeeb tshuaj uas zoo sib xws, Bondronate tuaj yeem raug txawm los ntawm cov poj niam uas siv cov tshuaj hormone kho thaum lub cev ntas. Hauv qee kis, cov tshuaj no tau muab kho rau cov neeg mob uas muaj cov tshuaj hypercalcemia .
- Bisphosphonate Ethidronate sodium yog tshuaj rau cov kab mob hauv lub cev thiab tau pov thawj nws tus kheej hauv txoj kev kho mob ntawm cov kab mob uas tau tshwm sim rau cov keeb kwm ntawm oncology.
- Clodronic acid yog siv los xaiv ua puas tsuaj macrophages. Qhov tshuaj no zoo kawg nkaus anesthetizes.
- Tshuaj Tiludronate tau sau tseg rau cov neeg mob uas muaj cov pob txha mos dhau los ua kom lawv ceev tau sai npaum li sai tau.
- Risedronate tiv thaiv pob txha ntawm qaum thiab lub caj dab femoral - kev raug mob ntau tshaj plaws uas tshwm sim hauv cov poj niam postmenopausal.
Ntaos ntawm txoj kev kho kab mob ntsws bioposphonate
Nws yog ib qho tseem ceeb kom to taub hais tias kev ntxiv dag zog ntawm cov pob txha tsis yog tus txheej txheem ceev tshaj plaws. Thiab txawm tias cov kab ntsaum los ua haujlwm sai sai, lawv tsis tau daws qhov teeb meem li ob peb hnub. Yog li, pib txoj kev kho mob, tus neeg mob yuav tsum tau npaj nws tus kheej rau qhov tseeb tias chav kawm zoo tshaj plaws yuav kav ib xyoo. Feem ntau bisphosphonates noj ob peb xyoos. Tab sis qhov kev tshwm sim ntawm kev kho mob no ua rau lawv zoo.
Cov no yog cov tshuaj muaj zog heev. Tag nrho cov kev npaj muaj bacteriophonates tsis yaj zoo heev hauv lub cev. Yog li ntawd,
- Nws yog qhov zoo tshaj rau haus dej kabmob ntses thaum sawv ntxov nyob rau ntawm lub plab yam tsawg ib teev thiab ib nrab ua ntej noj mov.
- Nws pom zoo kom haus ib ntsiav tshuaj nrog dej ntau. Siv lwm cov kua (tshuaj yej, txiv mab txiv ntoo, mis nyuj) yog tsis txaus nyiam.
- Rau cov ntsiav tshuaj tau yooj yim mus rau qhov chaw uasi, tom qab noj nws dua li ib teev los sis ib nrab rau zaum los sawv ntsug.
Qhov feem ntau tsim npaj thiab nws cov tshuaj yuav tsum yog xaiv los ntawm ib tug kws kho mob tshwj xeeb tom qab qhov kev ntsuam xyuas ua tiav.