Pradax yog ib hom yeeb tshuaj uas muaj rau cov tshuaj anticoagulant thiab cov tshuaj antithrombotic. Lawv siv nws nyob rau hauv orthopedics thiab traumatology nyob rau hauv lub sij hawm tom qab rau cov kev tiv thaiv ntawm venous thromboembolism.
Feasibility ntawm kev siv Pradax
Lub ntsiab yam khoom tseem ceeb ntawm cov tshuaj no yog dabigatran etexilate. Vim li no, qhov kev ua kom muaj mob thrombin suppressed tom qab thov Pradax npaj. Dabigatran etexilate sai absorbed thiab transformed rau dabigatran (reversible tib neeg thrombin inhibitor) thaum lub caij hydrolysis. Kev siv tshuaj ntawm cov tshuaj yog txo los ntawm 20% yog tias qhov hnyav ntawm tus neeg muaj ntau tshaj 120 kg, thiab nce mus ntxiv 25% nrog lub cev ntawm tus neeg mob tsawg tshaj 48 kg.
Cov kev qhia rau kev siv Pradax yog:
- kev tiv thaiv ntawm venous thromboembolism;
- kev tiv thaiv ntawm ntau yam kev sib txheeb muaj zog tromboembolism ;
- kev tiv thaiv ntawm cov kab mob hauv cov neeg mob uas muaj atrial fibrillation.
Kev siv Pradax yog qhia kom pom tag nrho cov neeg mob nrog kev kuaj mob tom qab orthopedic kev khiav hauj lwm, txij thaum tag nrho cov coagulants niaj hnub no tshuaj yog qhov zoo tshaj plaws. Tsis tas li ntawd, cov tshuaj no tau sau tseg tom qab lub hauv caug txha endoprosthetics. Txais tos kom ceev nrooj ntawm lub cev yuav tsum pib 1-4 teev tom qab kawg ntawm kev khiav hauj lwm.
Contraindications mus rau siv ntawm Pradaxi
Txawm hais tias koj muaj kev qhia txog kev siv Pradax cov tshuaj, koj siv tsis tau rau kev kho mob rau qhov mob siab rau tej yam khoom ntawm cov tshuaj. Tsis txhob pib noj cov tshuaj uas muaj mob hnyav tsis zoo, tsis tuaj yeem los yog ua tsis zoo ntawm homeostasis thiab nrog qhov ntshav tseem ceeb.
Contraindications rau kev siv Pradax kuj:
- impaired daim siab ua haujlwm;
- raug mob ntawm caj pas thiab hlwb;
- malignant neoplasms;
- intracranial hemorrhage;
- txoj hnyuv rwj;
- intracerebral vascular ntshawv siab.
Nws tsis pom zoo kom siv cov tshuaj no ib txhij nrog cov neeg sawv cev ntawm tshuaj tua kabmob. Txoj kev sib txuam no yog ib qho txaus ntshai rau lub neej, vim nws loj tuaj yeem ua rau muaj feem ntshav ntawm yuav luag threefold. Yog tias muaj pov thawj rau kev siv Pradax thiab tus kws kho mob tau txiav txim siab los muab cov tshuaj no, ces nws yuav tsum tshem tawm cov kev xav ntawm lwm yam tshuaj tiv thaiv kab mob. Nws tsis pom zoo los kho cov tshuaj rau cov neeg mob hnub nyoog qis dua 18 xyoo, vim tias tsis muaj cov ntaub ntawv tshawb fawb txog cov kev siv ntawm lub hnub nyoog no.