Allopurinol - analogues

Allopurinol thiab nws cov analogs yog cov tshuaj uas tau sau nrog nce uric acid hauv lub cev - hyperuricemia. Tus kab mob feem ntau ua rau gout. Cov tshuaj siv pom zoo rau cov neeg mob uas tsis tuaj yeem tswj tau noj haus ib zaug xwb.

Allopurinol ntsiav tshuaj kuj tau sau rau cov neeg uas tau tsim cov kab mob pob zeb thiab cov hlab ntsws. Nws yog siv rau cov neeg laus thiab cov menyuam yaus tshaj 15 xyoos uas muaj cov cim qhia txog cov kab mob no rau ntawm keeb kwm ntawm cov kab mob ntshav dawb , thiab rau cov neeg muaj lub cev tsis muaj zog enzymatic.

Yuav ua li cas los hloov Allopurinol nrog gout?

Cov qauv analog ntawm Allopurinol:

Lub ntsiab tivthaiv yog oxypurinol, uas suppresses conversion ntawm hypoxanthine rau xanthine, thiab ces mus rau uric acid. Nrog kev pab los ntawm kev siv yeeb siv tshuaj, theem ntawm qhov kawg nyob rau hauv cov zis thiab lub circulatory system txo. Qhov no tiv thaiv qhov txuam nrog cov kwj deg ntawm lub cev thiab txhawb nqa lawv cov resorption. Tus nqi ntawm cov kua qaub yuav pib ua rau tsuas yog hnub plaub ntawm kev noj tshuaj. Qhov siab tshaj plaws yog tshwm sim tom qab ob lub lim tiam.

Purinol kuj yog ib qho qauv analog ntawm Allopurinol. Thaum lub sij hawm kev tswj ntawm tshuaj, lub synthesis ntawm uric acid txo, uas ua rau nws txo nyob rau hauv lub kua tawm ntawm lub cev. Tsis tas li ntawd, cov tshuaj uas twb muaj lawm twb tau muab pov tseg lawm thiab lawv rov qab ua rau lub raum thiab cov ntaub so ntswg tiv thaiv. Thaum tau txais Purinol, qhov tso tawm ntawm xanthine thiab hypoxanthine nyob rau hauv cov zis nce. Cov nyhuv ntawm cov tshuaj nyob ntawm seb qhov tshuaj uas tau muab rau.

Contraindications rau kev siv Allopurinol thiab nws cov analogues

Allopurinol thiab nws cov analogs, kws kho mob rau gout , muaj ntau qhov contraindications, uas tau tshwm sim hauv ib leeg. Yog li, piv txwv, muaj cov neeg mob uas tau tsim muaj mob bradycardia thiab mob ntshav siab. Qee zaum, muaj li no:

Yuav luag txhua zaus qhov no tau nrog nws los ntawm:

Tsawg dua - ua txhaum cai ntawm qhov tsis pom kev thiab kev tu plaub, paj hlwb, cataracts, kev nyuaj siab thiab coma.

Thaum kho, cov neeg mob uas muaj kev tsis haum tshuaj hauv daim tawv nqaij pob liab liab, hyperemia, pruritus, kub taub hau thiab kub taub hau. Qee zaum, cov neeg tsim tau kab npauj npaim thiab cov plaub hau tawg.

Yog tias tsim nyog, cov kws ua hauj lwm pom zoo kom tau noj tsuas yog Allopurinol, thiab yog tias koj xav tau los hloov nrog ib yam dab tsi, koj yuav tsum tsuas thov rau cov kev sib piv zoo. Txwv tsis pub, nws tuaj yeem cuam tshuam rau kev ua haujlwm ntawm lub siab thiab tag nrho cov kab mob hauv tag nrho.